Description

Artesunate 30mg Injection (Habinate) is an antimalarial medication used to treat severe malaria caused by *Plasmodium falciparum*. It is a derivative of artemisinin and is administered intravenously or intramuscularly, making it suitable for patients who cannot take oral medications due to severe illness. ([tripplexpharmacy.com](https://tripplexpharmacy.com/p/cm48ko1eq0049107neum4cpgj?utm_source=openai))

**Composition:**
Each vial contains 30 mg of artesunate powder. The reconstitution involves adding 0.5 ml of sodium bicarbonate injection (5% w/v) to the vial, followed by 2.5 ml of sodium chloride injection (0.9% w/v) for intravenous use or 1 ml for intramuscular use. ([admin.greenbook.nafdac.gov.ng](https://admin.greenbook.nafdac.gov.ng/uploadImage/smpc_files/2024/03/23/202403239ca4412b-eb0e-534a-aa35-82d59d8b0d99.pdf?utm_source=openai))

**Indications:**
Artesunate 30mg Injection is indicated for the treatment of severe malaria caused by *Plasmodium falciparum* in adults and children. ([extranet.who.int](https://extranet.who.int/prequal/sites/default/files/whopar_files/MA089part4.pdf?utm_source=openai))

**Dosage and Administration:**
The recommended dosage regimen is:
– Loading dose: 2.4 mg/kg body weight administered intravenously or intramuscularly at 0, 12, and 24 hours.
– Maintenance dose: 1.2 mg/kg body weight once daily until the patient can tolerate oral antimalarial therapy.

The reconstituted solution should be administered as a slow intravenous bolus over 2-3 minutes. It is not recommended to administer the solution via continuous intravenous infusion. ([tripplexpharmacy.com](https://tripplexpharmacy.com/p/cm48ko1eq0049107neum4cpgj?utm_source=openai))

**Storage:**
Store Artesunate 30mg Injection in the original packaging, below 30°C, and protect from direct sunlight. Do not store in a refrigerator or freezer. The reconstituted and diluted solutions should be used immediately and not stored for later use. ([extranet.who.int](https://extranet.who.int/prequal/sites/default/files/whopar_files/MA089part3.pdf?utm_source=openai))

**Side Effects:**
Common side effects may include:
– Headache
– Dizziness
– Nausea or vomiting
– Abdominal pain
– Cough
– Decreased white blood cell count (lymphocytes)
– Reduced reticulocyte count
– Fever
– Taste change
– Ringing in the ears (tinnitus)
– Rash

Serious side effects, though rare, can include hemolytic anemia, jaundice, and acute respiratory distress syndrome. ([tripplexpharmacy.com](https://tripplexpharmacy.com/p/cm48ko1eq0049107neum4cpgj?utm_source=openai))

**Contraindications:**
Artesunate 30mg Injection is contraindicated in patients with known hypersensitivity to artesunate or any of its components. ([tripplexpharmacy.com](https://tripplexpharmacy.com/p/cm48ko1eq0049107neum4cpgj?utm_source=openai))

**Precautions:**
Use with caution in patients with a history of severe allergic reactions. Monitor for post-treatment hemolytic anemia for up to four weeks after treatment. Use during pregnancy should be considered only if the potential benefit justifies the potential risk to the fetus. ([tripplexpharmacy.com](https://tripplexpharmacy.com/p/cm48ko1eq0049107neum4cpgj?utm_source=openai))

**Note:**
Artesunate 30mg Injection should only be administered under the supervision of qualified healthcare professionals. The dosage and duration of treatment should be tailored to the individual patient’s needs and clinical response.