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Description
Flibanserin 100 mg tablets are a medication used primarily for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women.
Primary Medical Uses:
– Treatment of generalized hypoactive sexual desire disorder (HSDD) in premenopausal women, characterized by a persistent or recurrent lack of sexual desire causing distress or interpersonal difficulty.
Drug Class or Type:
– Centrally acting multifunctional serotonin agonist and antagonist (a serotonergic agent).
General Mechanism of Action:
– Flibanserin works by modulating neurotransmitters in the brain, particularly by agonizing serotonin 5-HT1A receptors and antagonizing 5-HT2A receptors, which leads to an increase in dopamine and norepinephrine levels. These changes can help improve sexual desire.
Common Forms:
– Oral tablets, typically 100 mg strength.
Dosage Instructions:
– The recommended dose is one 100 mg tablet taken once daily at bedtime.
– It should be taken consistently each night to maintain effect.
– Flibanserin is not intended for use in men or postmenopausal women.
Side Effects, Contraindications, or Interactions:
– Common side effects include dizziness, nausea, fatigue, somnolence, and dry mouth.
– It can cause low blood pressure and fainting, especially when combined with alcohol or certain medications.
– Contraindicated in patients with liver impairment, or those using alcohol, strong CYP3A4 inhibitors, or certain other medications.
– Caution is advised due to potential drug interactions and adverse effects on blood pressure.
Use under medical supervision is essential for proper dosing, monitoring, and to manage possible side effects or interactions.
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