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Description
Flotac 75 mg capsules are a combination medication containing diclofenac and cholestyramine.
**Primary Medical Uses:**
– Treatment of pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
– Management of acute musculoskeletal disorders.
**Drug Class or Type:**
– Nonsteroidal anti-inflammatory drug (NSAID).
**General Mechanism of Action:**
– Diclofenac inhibits cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased production of prostaglandins, which are chemicals responsible for pain and inflammation.
– Cholestyramine is included to enhance the absorption and bioavailability of diclofenac.
**Common Forms:**
– Oral capsules, typically containing 75 mg of diclofenac and 4 g of cholestyramine.
**Dosage Instructions:**
– The usual adult dose is one capsule taken once or twice daily, depending on the severity of the condition and the physician’s recommendation.
– It is advisable to take the capsules with a full glass of water and not to exceed the prescribed dosage.
– The safety and efficacy of Flotac in children have not been established. Use in pediatric patients should be determined by a healthcare provider.
**Side Effects, Contraindications, or Interactions:**
– Common side effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain.
– Serious side effects can include cardiovascular events, liver dysfunction, and gastrointestinal bleeding.
– Contraindicated in patients with known hypersensitivity to diclofenac, cholestyramine, or any component of the formulation.
– Caution is advised in patients with a history of gastrointestinal ulcers, bleeding disorders, or cardiovascular disease.
– May interact with other NSAIDs, anticoagulants, and medications affecting liver function.
Use under medical supervision is important to ensure proper dosing and monitoring for side effects or interactions.
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