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Description
Fluconazole capsules 150 mg are an antifungal medication used to treat and prevent fungal infections.
Primary Medical Uses:
– Treatment of fungal infections such as candidiasis (including oral thrush and esophageal candidiasis), cryptococcal meningitis, and other systemic fungal infections.
– Prevention of fungal infections in immunocompromised patients.
Drug Class or Type:
– Azole antifungal.
General Mechanism of Action:
– Fluconazole works by inhibiting an enzyme necessary for the synthesis of ergosterol, an essential component of fungal cell membranes, which compromises the integrity of the fungal cell membrane and leads to fungal cell death.
Common Forms:
– Capsules, commonly in 50 mg, 100 mg, and 150 mg strengths.
Dosage Instructions:
– Dosage depends on the type and severity of infection.
– Usually taken orally once daily, with or without food.
– The 150 mg capsule is often used as a single dose for certain infections like vaginal yeast infections or as part of a longer treatment course for other fungal infections.
Side Effects, Contraindications, or Interactions:
– Common side effects include headache, nausea, abdominal pain, diarrhea, and rash.
– Serious side effects may involve liver toxicity, allergic reactions, and heart rhythm changes.
– Contraindicated in patients with known hypersensitivity to fluconazole.
– May interact with medications such as warfarin, oral hypoglycemics, certain antiepileptics, and others metabolized by the liver.
Medical supervision is important to determine the appropriate dose and monitor for side effects and drug interactions.
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