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Description
Fluconazole (Denk) 150 mg capsules are an antifungal medication used to treat and prevent fungal infections.
Primary Medical Uses:
– Treatment of fungal infections such as candidiasis (including oral, esophageal, and vaginal infections), cryptococcal meningitis, and other systemic fungal infections.
– Prevention of fungal infections in immunocompromised patients.
Drug Class or Type:
– Azole antifungal.
General Mechanism of Action:
– Fluconazole works by inhibiting an enzyme necessary for the synthesis of ergosterol, an essential component of fungal cell membranes, disrupting the membrane and leading to fungal cell death.
Common Forms:
– Oral capsules, commonly available in strengths such as 50 mg, 100 mg, and 150 mg.
Dosage Instructions:
– The dosage depends on the type and severity of the infection.
– The 150 mg capsule is often used as a single dose for certain infections like vaginal yeast infections, or as part of a longer treatment course for more severe fungal infections.
– Capsules are usually taken orally once daily, with or without food.
Side Effects, Contraindications, or Interactions:
– Common side effects include headache, nausea, abdominal pain, diarrhea, and rash.
– Serious side effects can include liver toxicity, allergic reactions, and heart rhythm changes.
– Contraindicated in patients with known hypersensitivity to fluconazole.
– May interact with medications such as warfarin, oral hypoglycemics, certain antiepileptics, and other drugs metabolized by liver enzymes.
Use under medical supervision is important to ensure proper dosing and monitoring for side effects or interactions.
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