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Description
Glucophage 1000mg Tablet contains metformin as its active ingredient.
Primary Medical Uses:
– Used to improve blood sugar control in adults with type 2 diabetes mellitus.
– Helps manage blood glucose levels as part of a comprehensive diabetes care plan that includes diet and exercise.
Drug Class or Type:
– Oral antidiabetic drug, classed as a biguanide.
General Mechanism of Action:
– Metformin decreases hepatic glucose production.
– Enhances insulin sensitivity to improve peripheral glucose uptake and utilization.
Common Forms:
– Oral tablet, typically available in 500 mg and 1000 mg strengths.
Dosage Instructions:
– Often taken once or twice daily with meals to reduce gastrointestinal discomfort.
– Dosage should be individualized based on therapeutic response and tolerance.
– Starting dose usually begins at 500 mg or 850 mg per day, with gradual increments to minimize side effects.
– Maximum recommended dose is generally up to 2000-2500 mg per day, divided doses.
Side Effects, Contraindications, or Interactions:
– Common side effects include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.
– Rare but serious risk of lactic acidosis, especially in patients with impaired kidney function or other risk factors.
– Contraindicated in patients with severe renal impairment, metabolic acidosis, diabetic ketoacidosis, and hypersensitivity to metformin.
– Use caution with other drugs affecting renal function or that may increase risk of hypoglycemia.
Glucophage 1000mg is a commonly prescribed medication to help control high blood sugar in patients with type 2 diabetes. Regular monitoring and adherence to prescribed doses are essential for safe and effective treatment.
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