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Description
Glucovance 500/2.5mg is a prescription medication used to manage type 2 diabetes mellitus in adults. It contains two active ingredients: metformin hydrochloride (500 mg) and glibenclamide (2.5 mg).
Primary Medical Uses:
– To improve blood sugar control in adults with type 2 diabetes.
Drug Class or Type:
– Combination oral antidiabetic agent.
General Mechanism of Action:
– Metformin decreases hepatic glucose production and improves insulin sensitivity.
– Glibenclamide stimulates insulin release from the pancreas.
Common Forms:
– Oral tablet.
Dosage Instructions:
– Usually taken once or twice daily with meals.
– Dosage should be tailored individually, considering effectiveness and tolerance.
– Starting at lower doses may reduce gastrointestinal side effects and risk of hypoglycemia.
– Maximum allowable daily doses should not be exceeded.
Side Effects, Contraindications, or Interactions:
– Side effects may include gastrointestinal disturbances (nausea, diarrhea), hypoglycemia, and possible allergic reactions.
– Should not be used in patients with known allergies to metformin or glibenclamide, type 1 diabetes, diabetic ketoacidosis, severe kidney or liver impairment.
– Alcohol intake should be limited due to increased risk of hypoglycemia and lactic acidosis.
– Regular monitoring of blood glucose and renal function is recommended during therapy.
Glucovance 500/2.5mg is intended for use alongside diet and exercise as part of a comprehensive diabetes management plan.
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