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Description
Human Albumin 20% 100 mL is a sterile solution containing 20 grams of human albumin per 100 milliliters. Albumin is a protein found in human blood plasma, playing a crucial role in maintaining oncotic pressure, which helps regulate the distribution of fluids between blood vessels and tissues.
**Primary Medical Uses:**
– **Volume Expansion:** Rapidly increases plasma volume in cases of hypovolemia due to trauma, surgery, or burns.
– **Hypoalbuminemia Treatment:** Addresses low serum albumin levels associated with conditions like nephrotic syndrome, liver cirrhosis, and protein-losing enteropathies.
– **Plasma Exchange:** Serves as a replacement fluid during therapeutic plasma exchange procedures.
**Drug Class or Type:**
– Plasma-derived colloid solution.
**General Mechanism of Action:**
– By increasing plasma volume, human albumin helps restore and maintain circulating blood volume, thereby improving tissue perfusion and oxygen delivery.
**Common Forms:**
– Intravenous solution in 100 mL vials.
**Dosage Instructions:**
– Administered intravenously; the dosage and infusion rate depend on the patient’s clinical condition, body weight, and ongoing losses.
– For hypovolemia, an initial dose of 20 grams (100 mL) may be given, with adjustments based on the patient’s response.
– For hypoalbuminemia, doses are typically calculated based on body weight, not exceeding 2 grams per kilogram of body weight per day.
– Albumin solutions should not be diluted with water for injections, as this may cause hemolysis in recipients.
Human Albumin 20% 100 mL is intended for use under the supervision of healthcare professionals to effectively manage conditions requiring volume expansion and oncotic support.
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