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Description
Lactulose Solution 100mls (Laclose) is a medication used primarily for the treatment of constipation and hepatic encephalopathy.
Primary Medical Uses:
– Relief of constipation by softening stools and promoting bowel movements.
– Management of hepatic encephalopathy by reducing blood ammonia levels.
Drug Class or Type:
– Osmotic laxative.
General Mechanism of Action:
– Lactulose is a synthetic sugar that is not absorbed in the intestines. It draws water into the bowel, softening stools and facilitating easier bowel movements.
– In hepatic encephalopathy, lactulose reduces the absorption of ammonia from the gut, lowering blood ammonia levels and improving neurological function.
Common Forms:
– Oral solution, typically packaged in 100ml bottles.
Dosage Instructions:
– For constipation: Usually 15-30ml daily, adjusted to produce 2-3 soft stools per day.
– For hepatic encephalopathy: Initial doses may be higher, often 30-45ml three times daily, adjusted based on response.
– The solution is taken by mouth, with or without food.
– Dosage should be individualized by a healthcare professional.
Side Effects, Contraindications, or Interactions:
– Common side effects include bloating, gas, stomach cramps, nausea, and diarrhea.
– Contraindications include galactosemia and known allergy to lactulose.
– Use cautiously in patients with diabetes or on restricted sugar diets.
– Prolonged use should be under medical supervision.
– Possible interactions with other medications; consult a healthcare provider for guidance.
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