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Description
Letrozole Tab 2.5mg (Denk) contains letrozole, a medication used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Primary Medical Uses:
– Treatment of breast cancer by lowering estrogen levels to slow the growth of hormone-sensitive tumors.
– Sometimes used off-label for ovulation induction in certain fertility treatments.
Drug Class or Type:
– Aromatase inhibitor.
General Mechanism of Action:
– Letrozole works by inhibiting the enzyme aromatase, which converts androgens into estrogen. Reduced estrogen levels help inhibit the growth of estrogen-dependent breast cancer cells.
Common Forms:
– Oral tablets, typically 2.5 mg strength.
Dosage Instructions:
– Usually taken once daily, with or without food.
– Tablets should be swallowed whole.
– Treatment duration and dosage depend on the medical condition and doctor’s advice.
Side Effects, Contraindications, or Interactions:
– Common side effects may include hot flashes, joint pain, fatigue, nausea, and increased sweating.
– Serious side effects can include bone thinning (osteoporosis) and increased risk of fractures.
– Contraindicated in pregnancy and breastfeeding.
– Use caution in patients with liver impairment.
– Drug interactions can occur with other medications influencing estrogen levels or liver metabolism.
Use under medical supervision with regular monitoring.
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