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Description
Lisinopril + Hydrochlorothiazide 10mg/12.5mg (UK generic) is a combination medication used primarily to treat high blood pressure (hypertension).
Primary Medical Uses:
– The combination is used to lower high blood pressure, reducing the risk of stroke, heart attack, and kidney problems.
Drug Class or Type:
– Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor.
– Hydrochlorothiazide is a thiazide diuretic.
General Mechanism of Action:
– Lisinopril relaxes and widens blood vessels by inhibiting an enzyme that causes vessel narrowing.
– Hydrochlorothiazide helps remove excess salt and water from the body through increased urine output, reducing blood volume and pressure.
Common Forms:
– Oral tablets containing 10mg of lisinopril and 12.5mg of hydrochlorothiazide.
Dosage Instructions:
– Usually taken once daily, with or without food.
– Dosage may be adjusted by a healthcare professional based on individual response and condition.
– Follow prescribed instructions carefully.
Side Effects, Contraindications, or Interactions:
– Possible side effects include dizziness, headache, persistent cough, fatigue, and increased urination.
– Serious effects can include low blood pressure, elevated potassium levels, kidney problems, or allergic reactions.
– Contraindicated in patients with a history of angioedema related to ACE inhibitors.
– Can interact with potassium supplements, other blood pressure medications, lithium, and nonsteroidal anti-inflammatory drugs (NSAIDs).
– Regular monitoring of blood pressure, kidney function, and electrolyte levels is recommended during treatment.
Use as directed by a healthcare professional.
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