Description

Pabiovite High Potency 1 & 2 Injection is a combination vitamin preparation used to treat or prevent deficiencies of water-soluble vitamins B and C. It is particularly indicated in conditions such as acute or chronic alcoholism, post-infection recovery, hyperemesis gravidarum, anorexia, psychiatric states, hemodialysis, convalescence, cerebrovascular disease, cardiovascular disorders, and as an adjunct in hepatitis treatment. ([fdaghana.gov.gh](https://fdaghana.gov.gh/wp-content/uploads/2025/07/PABIOVITE-High-Potency-1-2-Injection-SmPC.pdf?utm_source=openai))

The injection consists of two ampoules:

– **Ampoule 1** contains:
– Thiamine Hydrochloride BP: 250 mg
– Riboflavin Sodium Phosphate BP: 4 mg
– Pyridoxine Hydrochloride BP: 50 mg
– Nicotinamide BP: 160 mg
– Water for Injection BP: q.s.

– **Ampoule 2** contains:
– Ascorbic Acid BP: 500 mg
– Glucose BP: 1000 mg
– Water for Injection BP: q.s. ([fdaghana.gov.gh](https://fdaghana.gov.gh/wp-content/uploads/2025/07/PABIOVITE-High-Potency-1-2-Injection-SmPC.pdf?utm_source=openai))

The recommended dosage involves mixing equal volumes from Ampoule 1 and Ampoule 2 just before administration. Dilute 2-3 pairs (1 pair = Ampoule 1 + Ampoule 2) in 50-100 ml of physiological saline or 5% glucose. Administer by slow intravenous injection over 10 minutes or by drip infusion over 30 minutes, every 8 hours, or as directed by a physician. This medication should be used under medical supervision only. ([fdaghana.gov.gh](https://fdaghana.gov.gh/wp-content/uploads/2025/07/PABIOVITE-High-Potency-1-2-Injection-SmPC.pdf?utm_source=openai))

Common side effects may include allergic reactions (e.g., rash, itching, anaphylaxis), dizziness, nausea, vomiting, flushing, or injection site reactions. ([fdaghana.gov.gh](https://fdaghana.gov.gh/wp-content/uploads/2025/07/PABIOVITE-High-Potency-1-2-Injection-SmPC.pdf?utm_source=openai))

Pabiovite High Potency 1 & 2 Injection is contraindicated in individuals with hypersensitivity to any component of the formulation. Caution is advised in cases of pregnancy, breastfeeding, or renal impairment. Monitoring for hypersensitivity is essential; discontinue use if severe reactions occur. This product is not intended for intramuscular use. ([fdaghana.gov.gh](https://fdaghana.gov.gh/wp-content/uploads/2025/07/PABIOVITE-High-Potency-1-2-Injection-SmPC.pdf?utm_source=openai))

Before using Pabiovite High Potency 1 & 2 Injection, consult a healthcare professional, especially if you are pregnant, breastfeeding, or have underlying health conditions. Store the injection in a cool, dry place, protected from light, and keep it out of reach of children. Do not freeze. Use immediately after reconstitution. ([fdaghana.gov.gh](https://fdaghana.gov.gh/wp-content/uploads/2025/07/PABIOVITE-High-Potency-1-2-Injection-SmPC.pdf?utm_source=openai))