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Description
Tenofovir Alafenamide 25mg (Mylan) is an antiviral medication.
Primary Uses:
– Treatment of HIV-1 infection in adults and pediatric patients
– Treatment of chronic hepatitis B virus (HBV) infection
Drug Class or Type:
– Nucleotide reverse transcriptase inhibitor (NRTI)
General Mechanism of Action:
– Tenofovir alafenamide is a prodrug of tenofovir that inhibits reverse transcriptase, preventing viral replication by blocking an enzyme essential for the virus.
Common Forms:
– Oral tablets, 25 mg strength, typically in blister packs of 30 tablets
Dosage Instructions:
– The usual dosage for treatment of HIV or HBV is one 25 mg tablet once daily.
– Tablets can be taken with or without food.
– Dosage may vary based on the patient’s condition and concomitant medications as directed by a healthcare provider.
Side Effects, Contraindications, or Interactions:
– Common side effects include nausea, headache, fatigue, and abdominal pain.
– Compared to tenofovir disoproxil fumarate, tenofovir alafenamide generally has a better safety profile with less impact on kidney function and bone mineral density.
– Contraindicated in patients with hypersensitivity to tenofovir alafenamide or any tablet components.
– Monitoring of renal function is recommended during treatment.
– Potential drug interactions may occur with other antiretroviral or nephrotoxic drugs.
Store in a cool, dry place away from direct sunlight and out of reach of children.
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