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Description
UPERIO Tab 50 mg contains a combination of Valsartan and Sacubitril.
Primary Uses:
– Treatment of heart failure with reduced ejection fraction to improve survival and reduce hospitalization.
– Helps in managing cardiovascular conditions by improving heart function.
Drug Class or Type:
– Combination of an angiotensin receptor blocker (ARB) and a neprilysin inhibitor.
General Mechanism of Action:
– Valsartan blocks angiotensin II receptors, causing blood vessel relaxation, reduced blood pressure, and decreased strain on the heart.
– Sacubitril inhibits neprilysin, an enzyme that breaks down natriuretic peptides, enhancing their beneficial effects like vasodilation and sodium excretion, which reduce blood volume and pressure.
Common Forms:
– Oral tablet, in this case, 50 mg strength combining both active ingredients.
Dosage Instructions:
– Dosage is individualized based on patient condition and response.
– Usually taken twice daily.
– Should be used under medical supervision with regular monitoring of blood pressure, kidney function, and electrolytes.
Side Effects, Contraindications, or Interactions:
– Common side effects may include low blood pressure, dizziness, high potassium levels, kidney impairment, and cough.
– Contraindicated in patients with a history of angioedema related to previous ACE inhibitor or ARB therapy.
– Not recommended during pregnancy.
– Use caution with other medications affecting blood pressure, potassium levels, or kidney function.
Use this medication only as prescribed by a healthcare professional.
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