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HALOPERIDOL DECANOATE INJ 50MG (HALDOL)

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Description

HALOPERIDOL DECANOATE INJ 50MG (HALDOL) is a long-acting injectable antipsychotic medication.

Primary Medical Uses:
– Management of chronic schizophrenia and other psychotic disorders.
– Used for patients who require maintenance treatment and have difficulty with oral medication adherence.

Drug Class or Type:
– Typical (first-generation) antipsychotic, butyrophenone derivative.

General Mechanism of Action:
– It works by blocking dopamine D2 receptors in the brain, which helps reduce psychotic symptoms such as hallucinations and delusions.
– The decanoate form is a slow-release ester that allows for extended duration of action.

Common Forms:
– Intramuscular injection, suspended in oil for slow release.

Dosage Instructions:
– Typically administered every 4 weeks or as directed by a healthcare professional.
– Dosage often starts at 50 mg every 4 weeks, adjusted according to patient response and tolerance.
– Initial treatment with oral haloperidol is usually recommended before starting the injectable form to assess tolerability.
– Injection should be given deep intramuscularly, usually in the gluteal muscle.

Side Effects, Contraindications, or Interactions:
– Common side effects include sedation, extrapyramidal symptoms (tremors, rigidity, restlessness), weight gain, and dry mouth.
– Risk of tardive dyskinesia and neuroleptic malignant syndrome with prolonged use.
– Contraindicated in patients with hypersensitivity to haloperidol or severe CNS depression.
– Caution in patients with cardiac conditions, seizures, or liver impairment.
– May interact with CNS depressants, anticholinergics, and drugs that prolong QT interval.

HALOPERIDOL DECANOATE INJ 50MG (HALDOL) is a long-acting injectable used for maintenance treatment of psychotic disorders by providing sustained dopamine receptor blockade.

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