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Description
Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) used for the short-term management of moderately severe acute pain that requires analgesia at the opioid level. It is typically prescribed for up to 5 days in adults, often following intravenous or intramuscular dosing.
**Common Forms:**
– Oral tablets, commonly available in 10 mg strength.
**Dosage Instructions:**
– Adults aged 17 to 64 years:
– Initial dose: 20 mg once.
– Subsequent doses: 10 mg every 4 to 6 hours as needed, not exceeding 40 mg per day.
– Adults aged 65 years and older, those with renal impairment, or weighing less than 50 kg:
– Initial dose: 10 mg once.
– Subsequent doses: 10 mg every 4 to 6 hours as needed, not exceeding 40 mg per day.
**Side Effects, Contraindications, or Interactions:**
– **Side Effects:** Common side effects may include nausea, abdominal pain, indigestion, headache, dizziness, and drowsiness. Serious side effects can occur, such as gastrointestinal bleeding, cardiovascular events, and renal impairment.
– **Contraindications:** Ketorolac is contraindicated in patients with active peptic ulcer disease, recent gastrointestinal bleeding, or known hypersensitivity to NSAIDs.
– **Drug Interactions:** Concurrent use with other NSAIDs, including over-the-counter medications like ibuprofen or naproxen, is not recommended due to an increased risk of adverse effects.
It is essential to use ketorolac at the lowest effective dose for the shortest duration necessary to minimize potential risks. Always consult a healthcare professional before starting or discontinuing any medication.
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