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Description
Xigduo XR (Dapagliflozin/Metformin) 5/1000 is a combination medication used to manage type 2 diabetes mellitus. It contains 5 mg of dapagliflozin and 1000 mg of metformin extended-release.
Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that helps lower blood sugar by preventing the kidneys from reabsorbing glucose back into the blood, leading to increased glucose excretion in urine.
Metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity, helping to lower blood sugar levels.
Xigduo XR is used to improve glycemic control in adults with type 2 diabetes, often in combination with diet and exercise.
It comes in extended-release tablet form, taken orally, usually once daily with food to reduce gastrointestinal side effects.
Dosage varies by individual patient needs and should be determined by a healthcare provider. It is important to follow prescribed dosing and not to exceed recommended amounts.
Common side effects can include urinary tract infections, genital infections, nausea, diarrhea, abdominal discomfort, and increased urination. Serious side effects may include lactic acidosis, dehydration, ketoacidosis, or kidney problems. It is contraindicated in patients with severe kidney impairment, metabolic acidosis, or hypersensitivity to its components. Monitoring of kidney function and blood sugar levels is important during treatment.
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